Analysis of prophages harbored by the human - adapted subpopulation 1 of Staphylococcus aureus CC 398 2 3
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چکیده
1 Service de Bactériologie et Hygiène, Centre Hospitalier Régional Universitaire, and 2 Réseau 8 des Hygiénistes du Centre, Centre Hospitalier Universitaire, F37044 Tours cedex, France. 9 3 Genomic Research Laboratory, University of Geneva Hospitals, CH-1211 Geneva 14, 10 Switzerland. 4 Service d'Hygiène, Centre Hospitalier Universitaire, and 5 UMR 6249 Chrono11 environnement, Université de Franche-Comté, F25030 Besançon cedex, France. 6 Laboratory 12 for Microbiology and infection Control, Amphia Hospital, Breda and VU University Medical 13 Center, Amsterdam, The Netherlands. 7 Service de Bactériologie et Hygiène Hospitalière, 14 Centre Hospitalier Universitaire, and 8 EA1254 Microbiologie-Risques Infectieux, Université 15 de Rennes 1, F35033 Rennes cedex, France. 16 17
منابع مشابه
Analysis of prophages harbored by the human-adapted subpopulation of Staphylococcus aureus CC398.
Staphylococcus aureus clonal complex 398 is a livestock-associated pathogen that poses a worldwide threat because of its ability to colonize and infect both humans and animals. We used high-resolution whole-genome microarrays, prophage profiling, immune evasion cluster characterization and whole-genome sequencing to investigate the roles of prophages in the emerging human-adapted subpopulation ...
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Staphylococcus aureus can colonize and infect both humans and animals, but isolates from both hosts tend to belong to different lineages. Our recent finding of bovine-adapted S. aureus showing close genetic relationship to the human S. aureus clonal complex 8 (CC8) allowed us to examine the genetic basis of host adaptation in this particular CC. Using total chromosome microarrays, we compared t...
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In recent years, there has been an increase in the number of livestock-associated methicillin resistant Staphylococcus aureus (LA-MRSA) clonal complex (CC) 398 recovered from S. aureus isolated animals in the UK. To determine possible origins of 12 LA-MRSA CC398 isolates collected after screening more than a thousand S. aureus animal isolates from the UK between 2013 and 2015, whole genome sequ...
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Nationwide surveillance identified 10 human isolates of methicillin-resistant Staphylococcus aureus clonal complex (CC) 398. Further typing in comparison with animal isolates identified 4 clusters: 1 related to a horse epidemic and 3 to persons who had no direct contact with animals or each other. These findings may indicate unrecognized community transmission.
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تاریخ انتشار 2013